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. 2018 Jul 6;13(7):e0198401. doi: 10.1371/journal.pone.0198401

Table 4. Anthropometric, maximal aerobic capacity, muscle function, and physical activity assessments before and after the intervention.

  Intensified HAES®-based intervention group (n = 39) Control group (n = 19)
Variable Pre Post CI (95%) ES Pre Post CI (95%) ES % Difference between delta change P value
Anthropometry
Body weight (kg) 90.7 (10.9) 90.1 (12.1) -1.09 to 1.45 -0.06 90.0 (10.5) 91.0 (11.1) -2.69 to 0.81 0.09 -0.87 0.301
Body mass index (kg/m2) 34.5 (2.7) 34.5 (3.2) -0.42 to 0.56 0.01 33.9 (3.1) 34.3 (3.3) -1.04 to 0.32 0.12 -0.83 0.309
Waist circumference (cm) 108.6 (8.6) 106.8 (8.1) -0.66 to 4.19 -0.21 109.0 (10.2) 107.8 (9.6) -2.18 to 4.54 -0.12 0.54 0.779
Hip circumference (cm) 119.4 (8.9) 119.0 (8.3) -2.96 to 1.42 -0.04 118.2 (7.0) 118.3 (8.6) -3.14 to 2.94 0.01 0.08 0.722
Waist to hip ratio 0.9 (0.06) 0.9 (0.06) -0.006 to 0.031 -0.19 0.9 (0.07) 0.9 (0.08) -0.017 to 0.034 -0.13 0.53 0.788
Maximal aerobic capacity
Time-to-VAT (sec) 222.3 (70.1) 226.3 (56.1) -30.35 to 22.45 0.06 243.3 (107.4) 203.4 (64.3) 2.67 to 79.73 -0.37 19.70ǒ 0.058
Time-to-RCP (sec) 454.7 (90.5) 502.6 (109.5)# -86.96 to -9.10 0.53 463.3 (105.0) 446.6 (101.9) -38.55 to 74.05 -0.16 15.02ǒ 0.059
Time-to-exhaustion (sec)* 625.4 (124.4) 671.4 (98.6) -79.19 to -12.76 0.37 656.7 (91.4) 678.7 (108.0) -71.18 to 26.01 0.24 3.84 0.429
VO2 VAT (mL/kg/min) 11.9 (3.0) 12.8 (2.7) -1.82 to 0.02 0.30 12.2 (4.1) 11.2 (2.1) -0.18 to 2.51 -0.26 17.83ǒ 0.014
VO2 RCP (mL/kg/min) 18.4 (2.9) 19.6 (3.6)# -2.39 to -0.19 0.44 18.6 (3.6) 17.3 (2.4)# -0.29 to 2.89 -0.34 14.65ǒ 0.010
VO2peak (mL/kg/min)* 22.0 (3.8) 24.0 (3.9)ø -2.89 to -1.07 0.52 22.5 (3.7) 22.2 (3.8) -0.93 to 1.74 -0.09 10.91ǒ 0.005
Muscle function tests
Timed Stands test (sec) 19.6 (4.0) 18.1 (4.3)# 0.29 to 3.10 -0.37 18.5 (4.4) 20.3 (5.8) -3.62 to 0.27 0.41 0.51ǒ 0.007
Timed-up-and-go test (sec)*ᶿ 6.0 (0.8) 6.4 (1.2) -0.87 to 0.19 0.52 7.3 (3.4) 8.1 (5.6) 1.54 to -0.08 0.24 -5.58 0.300
Physical activity levels
Sedentary time (min/day) 513.5 (88.1) 501.1 (101.3) -17.74 to 50.68 -0.14 538.5 (102.0) 517.0 (138.9) -45.23 to 55.89 -0.21 2.63 0.715
Light PA time (min/day) 325.0 (57.5) 325.0 (71.8) -24.18 to 28.19 0.00 328.2 (93.4) 369.2 (92.8) -74.82 to 2.46 0.44 -8.34 0.106
Total MVPA (min/day) 39.3 (20.7) 39.8 (20.7) -6.97 to 5.71 0.02 37.3 (21.6) 34.3 (23.5) -7.53 to 11.22 -0.14 5.11 0.662

Data are expressed as mean (SD), estimated mean of differences between pre and post values, 95% confidence interval (CI), Cohen’s d effect sizes (ES), and % delta differences [(post–pre from intervention)–(post–pre from control)]; expressed as mean ± SD). VAT, ventilatory anaerobic threshold; RCP, respiratory compensation point; VO, oxygen uptake; VO2peak, peak oxygen uptake; PA, physical activity; MVPA, moderate-to-vigorous physical activity.

P-values for group vs. time interaction.

ø Significant difference within group (P ≤ 0.05)

# Tendency for significance within group (P ≤ 0.10)

* Significant main effect of time (P ≤ 0.05)

ᶿ Significant main effect of group (P ≤ 0.05)

ǒ Significant difference between delta changes (P ≤ 0.05)