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. 2018 Jul 6;13(7):e0199698. doi: 10.1371/journal.pone.0199698

Fig 4. Effects of CRH on the correlation between plasma noradrenaline levels and the LF/HF ratio in men and women.

Fig 4

Plasma noradrenaline levels and LF/HF ratio during 40 mmHg distention (A) in male controls injected with placebo (n = 8) and CRH (n = 8). There were significant correlations in both groups (CRH, rho = 0.95, P < 0.01; placebo, rho = 0.91, P < 0.01). (B) Male patients with IBS injected with placebo (n = 8) and CRH (n = 8). (C) Female controls injected with placebo (n = 8) and CRH (n = 8). (D) Female patients with IBS injected with placebo (n = 8) CRH (n = 8). No significant correlations are shown in panels B, C, and D. IBS, irritable bowel syndrome; CRH, corticotropin-releasing hormone; LF, low frequency; HF, high frequency.