Table 2. Estimated iAUC differences using a bootstrapping method.

Difference	iAUC (95% CI)
Pre-OP versus POD 0	-0.0316 (-0.1175 to 0.0600)
Pre-OP versus POD 1	-0.0497 (-0.1454 to 0.0490)
Pre-OP versus POD 3	-0.0948 (-0.1830 to -0.0023)
Pre-OP versus POD 7	-0.1902 (-0.2691 to -0.0966)
POD 0 versus POD 1	-0.0182 (-0.1194 to 0.0856)
POD 0 versus POD 3	-0.0632 (-0.1639 to 0.0349)
POD 0 versus POD 7	-0.1586 (-0.2525 to -0.0658)
POD 1 versus POD 3	-0.0451 (-0.1399 to 0.0616)
POD 1 versus POD 7	-0.1404 (-0.2350 to -0.0421)
POD 3 versus POD 7	-0.0954 (-0.1870 to -0.0055)

Pre-OP, preoperative; POD, postoperative day; CI, confidence interval; iAUC, integrated area under the curve.