Table 2. Baseline sputum grading and drug susceptibility profile of new smear positive pulmonary TB patients.
Sputum smear and culture status | Total | |
---|---|---|
n (%) | ||
Sputum smear maximum | N = 1565 | |
grade* | Scanty positive | 127 (8) |
1+ | 578 (37) | |
2+ | 389 (25) | |
3+ | 471 (30) | |
Sputum culture status | N = 1565 | |
Any one culture Mtb positive | 1368 (87) | |
Culture negative | 166 (11) | |
Non-Tuberculous mycobacteria | 8 (<1) | |
Contaminated | 18 (1) | |
Sample insufficient | 5 (<1) | |
Sputum culture maximum | N = 1368 | |
grade | Colonies | 60 (4) |
1+ | 626 (46) | |
2+ | 494 (36) | |
3+ | 188 (14) | |
Drug susceptibility profile | N = 1304 | |
Susceptible to H, R, E | 1173(90) | |
Resistant to any drug | 131 (10) | |
Resistant to H | 77 | |
Resistant to R | 6 | |
Resistant to E | 27 | |
Resistant to HR | 3 | |
Resistant to HE | 7 | |
Resistant to ER | 1 | |
Resistant to HRE | 10 |
*Under RNTCP, as per standard of care, 2 sputum specimens are examined for smear. Grading by Ziehl Neelsen staining as follows: Negative—No AFB in 100 fields, Scanty = 1–9 AFB per 100 fields, 1+ = 10–99 AFB per 100 fields, 2+ = 1–10 AFB per field, 3+ = > 10 AFB per oil immersion field [6]. Grading by Auramine O Fluoresent staining is as follows: Negative—No AFB in 100 fields, 1+ = 1–10 AFB per 100 fields, 2+ = 11–100 AFB per 50 fields, 3+ = > 100 AFB per 20 fields [6].
H: Isoniazid, R: Rifampicin, E: Ethambutol