Table 3. Pairwise Spearman’s rank correlation coefficients for MIP, MCP, and cytokine concentrations in the amniotic fluid, cervicovaginal fluid, and maternal blood.
AF IL-6 | AF IL-8 | AF MCP-1 | CVF IL-6 | CVF IL-8 | CVF MCP-1 | CVF MIP-1α | CVF MIP-1β | MB MCP-1 | MB MIP-1α | |
---|---|---|---|---|---|---|---|---|---|---|
Amniotic fluid (AF) | ||||||||||
AF IL-8 | 0.955 b | |||||||||
AF MCP-1 | 0.913 b | 0.902 b | ||||||||
Cervicovaginal fluid (CVF) | ||||||||||
CVF IL-6 | 0.413 b | 0.416 b | 0.398 b | |||||||
CVF IL-8 | 0.555 b | 0.566 b | 0.531 b | 0.474b | ||||||
CVF MCP-1 | 0.569 b | 0.588 b | 0.615 b | 0.739b | 0.599 b | |||||
CVF MIP-1α | 0.515 b | 0.514 b | 0.502 b | 0.690b | 0.764 b | 0.809 b | ||||
CVF MIP-1β | 0.575 b | 0.550 b | 0.525 b | 0.711b | 0.710 b | 0.772 b | 0.940 b | |||
Maternal blood (MB) | ||||||||||
MB MCP-1 | 0.011 | -0.021 | 0.063 | 0.015 | -0.020 | 0.076 | 0.024 | 0.046 | ||
MB MIP-1α | -0.204 | -0.208 | -0.161 | -0.018 | -0.083 | -0.097 | -0.055 | -0.038 | -0.170 | |
MB MIP-1β | 0.098 | 0.005 | 0.020 | 0.025 | -0.065 | 0.034 | 0.073 | 0.180 | 0.324a | 0.172 |
AF, amniotic fluid; CVF, cervicovaginal fluid; MB, maternal blood; IL, interleukin; MCP-1, monocyte chemotactic protein-1; MIP, macrophage inflammatory protein.
a p < 0.01.
b p < 0.001.