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. 2018 May 11;42(2):946–956. doi: 10.3892/ijmm.2018.3670

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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PCNA⁺ BMSCs trapped in the kidneys of rats with ischemia/reperfusion-induced acute kidney injury. (A) Immunofluorescent staining images. Blue nuclei in the left panel indicate DAPI⁺ cells (BMSCs), red nuclei in the middle panel indicate PCNA⁺ cells, and purple nuclei (arrows) in the right panel indicate PCNA⁺DAPI⁺ cells (PCNA⁺ BMSCs). Scale bar, 20 µm. (B) Quantitative analysis. The ratio of PCNA⁺ BMSCs/BMSCs in the HO-1-BMSCs group is the highest. Results are presented as the mean ± standard deviation (n=10 rats). ^bP<0.05 vs. BMSCs group. PCNA, proliferating cell nuclear antigen; BMSCs, bone marrow-derived mesenchymal stem cells; HO-1, heme oxygenase-1; eGFP, enhanced green fluorescent protein.