Table II.
Clinicopathological features of stromal expression of TNC in patients with pancreatic ductal adenocarcinoma and high expression of ANX2.
| Clinicopathological feature | Total (n=49) | Stromal expression of TNC
|
P-value | |
|---|---|---|---|---|
| High (n=28) | Low (n=21) | |||
| Age (years) | 66.3±8.6 | 66.9±8.9 | 66.3±8.5 | NS |
| Gender (male/female) | 24/25 | 14/14 | 10/11 | NS |
| Tumor size (mm) | 28.4±8.4 | 29.6±7.8 | 26.6±9.1 | NS |
| N (0/1) | 11/37 | 3/24 | 8/13 | 0.026 |
| M (0/1) | 43/6 | 22/6 | 21/0 | 0.007 |
| UICC stage (IIA≥/≥IIB) | 10/39 | 2/26 | 8/13 | 0.007 |
| Residual tumor (R0/R1) | 35/14 | 19/9 | 16/5 | NS |
Data for age and tumor size are presented as the mean ± standard deviation. χ2 test was performed to determine statistical significance. UICC, International Union Against Cancer; ANX2, annexin II; TNC, tenascin C; NS, not significant.