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. 2018 May 14;42(2):831–838. doi: 10.3892/ijmm.2018.3676

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Copyright: © Mi et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of icariin on wound closure in vivo. The effect of icariin on closure of full-thickness excisional wounds was evaluated in rats. Each wound was treated with PBS or icariin daily for a total of 10 days. The animals were lightly anesthetized and the wound area was photographed and evaluated on the indicated days following injury. (A) Representative images of the wound site in the two treatment groups. (B) Quantification of the wound closure rate as % of wound area at different time point in comparison to the original wound area. ^*P<0.05 with comparisons indicated by lines.