Table 2.

Comparison of functional connectivity between three groups

	Talairach coordinates			No. of voxels	p, FEW corrected	Brain regions
No.	x	y	z
Left PCC seed, ANOVA between IGD, ibGD, and HC
1	−3	−42	33	796	<.001	Left cingulate gyrus, BA 31
2	3	−48	33		<.001	Right parietal precuneus, BA 31
3	−1	−50	33		<.001	Left parietal precuneus, BA 31
Right PCC seed, ANOVA between IGD, ibGD, and HC
4	3	−51	39	787	<.001	Right parietal precuneus, BA 7
5	−3	−50	51		<.001	Left parietal precuneus, BA 7
Left DLPFC seed, ANOVA between IGD, ibGD, and HC
6	−3	45	12	160	<.001	Left medial frontal gyrus, BA 10
7	18	12	0	25	<.001	Right lentiform nucleus, putamen
8	−36	−6	63	101	.007	Right middle frontal gyrus, BA 6
9	−51	−30	57	40	.004	Right postcentral gyrus, BA 2
Right DLPFC seed, ANOVA between IGD, ibGD, and HC
10	3	39	21	27	<.001	Right medial frontal gyrus, BA 9
11	24	12	3	36	<.001	Right lentiform nucleus, putamen
12	33	−12	−15	64	.009	Right hippocampus
13	−23	−10	−15	51	.009	Left amygdala
Left amygdala seed, ANOVA between IGD, ibGD, and HC
14	−21	−3	−15	163	.007	Left parahippocampal gyrus
Right amygdala seed, ANOVA between IGD, ibGD, and HC
15	30	3	−9	198	.006	Right sub-lobar insular

Note. FWE: family-wise error; PCC: posterior cingulate cortex; ANOVA: analysis of variance; DLPFC: dorsolateral prefrontal cortex; IGD: patient with Internet gaming disorder; ibGD: patient with Internet-based gambling disorder; HC: healthy comparison subjects; BA: Brodmann area.