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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Microbes Infect. 2017 Aug 31;19(11):536–545. doi: 10.1016/j.micinf.2017.08.007

Fig.1. Comparison of live organism shedding from the genital tract between mice with or without IL-6 deficiency following C. muridarum infection at a high dose.

Fig.1.

Groups of female C57BL/6J mice without (solid bar or square, wild type or Wt, n=8) or with (open bar or square, IL-6−/−,,n=7) deficiency in IL-6 were inoculated intravaginally with 5 × 105 IFUs of C. muridarum. Live C. muridarum organisms were monitored from the vaginal swabs taken on different days after the inoculation as shown along the X-axis. The results were expressed as Log10 IFUs (panel a) or % of mice that were still positive for shedding live organisms (b) as shown along the Y-axis. Note that IL-6−/− mice permitted more extensive C. muridarum colonization (on days 21, *p<0.05, Wilcoxon; 28 and 35, **p<0.01 after inoculation) than the Wt C57BL/6J mice in terms of both the extent of live organism shedding (a) and number of mice positive for live organism shedding (b), p<0.01 for both, Wilcoxon, area under curve or AUC, Wt vs. IL-6−/−.