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. 2018 Jul 6;13(7):e0199300. doi: 10.1371/journal.pone.0199300

Table 2. Study characteristics and key findings.

Author (year) Study country Setting Crisis type Crisis stage Target population Intervention Study design Key findings Quality
Family planning
Howard et al. (2008) Guinea Camp Armed Conflict Stabilised Refugee Development of a refugee led “Reproductive Health Group” Cross-sectional Those who reported RHG facilitators as their primary information source had non-significantly higher odds of being current users of contraception (OR = 1.3, 0.7–2.6, adjusted for parity, education, and partner approval of FP) High
Huber et al. (2010) Afghanistan Rural Armed Conflict Chronic General Population Health education, CHW delivery of injectable contraceptives Pre-Post Study The REACH Project achieved an increase of contraceptive use from 16% to 26%, over a period of 2 years in 13 provinces. The ACU Project increased contraceptive use by 24–27% in its three sites over 8 months Moderate
Casey et al. (2013) Uganda Rural Armed Conflict Stabilised IDP / General Population Mobile outreach and public health centre strengthening Cross-sectional Increased ever use of FP method 27.6% [23.5–32.2] to 47.3% [43.6–51.1], (aOR 2.23 [1.7–2.92] p<0.001). Unmet FP need 52.1% [48.5–55.6] to 35.7% [32–39.6], (aOR 0.47 [0.37–0.6], p<0.001) High
Curry et al. (2015) Multi-Country (Chad, DRC, Djibouti, Mali, Pakistan) Urban / Rural Armed Conflict / Natural Disaster Acute IDP / Refugee / General Population Training, facility supervision, supply of contraceptives, community mobilisation and awareness raising Cross-sectional Increase in new modern FP method users over time, notably for new users choosing long-acting and reversible contraceptives (78% in the DRC, 72% in Chad, and 51% in Mali, 29% in Pakistan). Moderate
Adam (2016) Sudan Camp Armed Conflict Chronic IDP Home counselling and awareness raising Cross-sectional Increased use of modern family planning methods (aOR 2.8, 95%CI 2.0–4.1) High
Raheel et al. (2012) Pakistan Urban Armed conflict Stabilised Refugee Subsidised healthcare (90% subsidies for doctor's visits, hospital visits, emergency care, free family planning, excluding prescriptions) Cross-sectional Reported use of contraceptives in subsidised group (54%) was more than double the use reported in the non-subsidised group (25%), (P<0.001); non-subsidised group more likely to use the pill (40.7%), subsidised group more likely to have tubal ligation (36.7%), p<0.001. High
PMTCT
Bannick-Mbazzi (2013) Uganda Rural Armed Conflict Chronic General Population Comprehensive PMTCT programme Cross-sectional Between 2004 and 2011, prevalence of HIV in children 6 weeks—18 months old declined from 10.3% to 5% (p = 0.01). Increase in number of HIV positive women delivering in a health facility (56% to 81%, p-0.033) High
HIV/Sexually transmitted infections (STIs)
Larsen et al. (2004) Sierra Leone Urban Armed Conflict Chronic General Population AIDS prevention programme–community outreach and education Pre-Post Study At post-intervention, 68 per cent of CSWs reported using a condom at their last sexual encounter as compared to only 38 per cent at baseline. At post-intervention 83 per cent reported having ever used a condom, as compared to 60 per cent at baseline. At post-intervention, 82 per cent of military respondents reported having ever used a condom up from 66 per cent in 2001, while the proportion of those who reported using a condom at last sexual intercourse increased from 39 per cent to 68 per cent of respondents. High
Casey et al. (2006) Sierra Leone Urban Armed Conflict Chronic IDP / General Population HIV prevention activities Pre-Post Study At baseline, fewer than one in five (15.6%) female youth reported condom use the last time they had sex, while nearly half (46.2%) reported this at post-intervention. Similarly, only one in four (24.8%) reported having ever used a condom at baseline as compared to nearly two in three (63.6%) at post-intervention. The proportion of male youth reporting having used a condom the last time they had sexual intercourse increased from 15.6% at baseline to 37.1%. While one in four (26.4%) respondents reported having ever used a condom at baseline, one in two (50.2%) reported having ever used a condom at post-intervention. High
Culbert et al. (2007) DRC Urban Armed Conflict Chronic General Population Initiation of anti-retroviral treatment Cohort 6 month median weight gain 2.5kg (0–5.5), 6 month medial CD4 gain 163 (82–232), 12 month mortality 7.9% (3.6%-12.1%), 12 month LTFU 5.4% (3.2–7.5) Moderate
O’Brien et al. (2010) Ten sub-Saharan African countries, Colombia, India Urban, Rural & Camp Armed Conflict & Natural Disaster Acute & Chronic IDP / Refugees / General Population HIV service integration Cross-sectional Median 12-month survival of 0.89 (95% CI 0.88–0.91) and a median 6-month CD4 gain of 129 cells/mm3 following the integration of HIV care and treatment programmes with other medical activities High
Logie et al. (2014) Haiti Camp Natural Disaster Chronic IDP Weekly psycho-educational and Peer Health Worker-led psycho-educational HIV-STI prevention Cohort Increase in condom use (AOR 4.05, 95% CI: 1.86, 8.83, p<0.001) High
Pregnancy & maternal and newborn health
Samai & Sengeh (1997) Sierra Leone Urban Armed Conflict Acute General Population Investments in vehicular referral system, community education, health facility improvements Pre-Post Study Service utilisation more than doubled in the period following initiation of the transport system. The case fatality rate declined from 20% to 10% in the post-intervention period. Moderate
McPherson et al. (2006) Nepal Urban & Rural Armed Conflict Stabilised General Population Community education, birth preparedness programme Pre-Post Study The proportion of women reporting one or more antenatal care visit increased from 60% to 84% (p<0.001), and use of postnatal care within six weeks of delivery increased from 45% to 72% (p<0.001). Changes in the use of a skilled birth provider were not statistically significant. High
Hadi et al. (2007) Afghanistan Rural Armed Conflict Chronic General Population Introduction of a community-based safe motherhood programme Pre-Post Study Pregnant women reached by CHW—40.3% in 2004 to 95.5% in 2006 (p<0.01); received antenatal care—37.3% in 2004 to 91.2% in 2006 (p<0.01); institutional delivery 31.3% to 55.2% (p<0.01) High
Purdin et al. (2009) Pakistan Urban & Rural Armed Conflict Chronic Refugee Establishing emergency obstetric care (EmOC) centres, community training on safe motherhood, linking primary health care with education on pregnancy danger signs and importance of skilled attendance at birth, improving health information system Cross-sectional The proportion of refugee births in an EmOC facility increased from 4.8% in 1996 to 67.2% in 2007. MMR reduced from 291 to 102 per 100,000 live births from 1st to 5th year of programme (95% CI 181 to 400); NMR reduced from 25 to 20.7 per 1000 live births from 1st to 7th year. Moderate
Turner et al. (2013) Thailand Camp Armed Conflict Chronic Refugee Development of a Special Care Baby Unit and associated training Cross-sectional NMR decreased from 21.8 deaths per 1000 live births to 10.7 deaths per 1000 live births (p = 0.03) between 2008 and 2011. Cause specific mortality fell in all of the four main causes of death overall: prematurity (19.3% to 4.8%), Early Onset Neonatal Sepsis (6.0% to 1.8%), congenital abnormality (60% to 22.2%) and jaundice (2.2% to 0.6%). Moderate
Adam (2015) Sudan Camp Armed Conflict Chronic IDP Home-based maternal health education Cross-sectional Maternal health education reduced odds of home birth (aOR 0.57) High
Adam et al. (2015) Sudan Camp Armed Conflict Chronic IDP Interpersonal communication and mass education campaigns Cross-sectional Education campaigns increased likelihood of at least 3 antenatal care visits (OR 8.8, 95% CI 6.4–12), healthcare-facility based delivery (OR 5.4, 95% CI 4.0–7.4), 1 or more postnatal care visits (OR 5.5, 95% CI 4.0–7.7). High
Groppi et al. (2015) South Sudan Urban & Rural Armed Conflict Chronic General Population Ambulance-based referral system Cross-sectional Facility-based deliveries increased in 2012 to 1089 (13.3% of expected deliveries in catchment area). 38.3% of women in need of EmOC received such care. CS proportion 0.6%. Moderate
Castillo et al. (2016) Philippines Urban & Rural Natural Disaster Early Recovery General Population Training of trainers and quality assessment workshops Pre-Post Study 24/7 skilled birth attendance (approx. 84% to 96%), kangaroo mother care (approx. 41% to 94%). High
Pham et al. (2016) Sudan Urban & Camp Armed Conflict Acute IDP / Refugee Staff training, primary healthcare service provision Cross-sectional Skilled birth attendance increased from 35.7% to 52.7% (p = 0.025) High
Sexual and gender-based violence
Gupta et al. (2013) Ivory Coast Rural Armed Conflict Acute General Population Gender dialogue groups, economic empowerment programme RCT VSLA + GDG less likely to report economic abuse than VSLA-only (OR 0.39, CI 0.25–0.6, p<0.0001); acceptance of justification towards violence was reduced (B = -0.97, CI -1.67, -0.28, p = 0.006). Highly adherent women in VSLA + GDG group less likely to report physical violence (aOR 0.45, CI 0.21–0.94, p = 0.04) High
Hossain et al. (2013) Ivory Coast Rural Armed Conflict Acute General Population Men’s discussion group RCT Men more likely to use one positive conflict management technique (aRR 1.3, CI 1.06–1.58); men involved in at least two household tasks (aRR 2.47, CI 1.24–4.9). High
Bass et al. (2013) DRC Rural Armed Conflict Chronic General Population Individual psychological support, group cognitive therapy RCT Individual support (HSCL-25 score 1.7+/-0.7 end of treatment, 1.5+/-0.6 6 months post-Tx; p<0.001; PTSD checklist 1.7+/-0.8 end of treatment, 1.5+/-0.7 6 months post-Tx, p<0.001; functional-impairment score 1.9+/-0.9 end of Tx, 1.8+/- 0.9 6 months post-Tx; p<0.001) and therapy groups (HSCL-25 score for depression and anxiety 0.8+/-0.6 end of treatment; 0.7+/-0.6 6 months post-Tx; p<0.001; PTSD checklist score end of treatment 0.8+/- 0.6 end of treatment, 0.7+/-0.6 6 months post-Tx, p<0.001; functional impairment score 0.8+/-0.07 end of Tx, 0.9+/-0.7 6 months post-Tx; p<0.0001) had significant improvements during treatment, with effects maintained at 6 months High
Interventions targeting outcomes across multiple SRH domains
Leigh et al. (1997) Sierra Leone Urban Armed Conflict Early Recovery General Population Skilled staff deployment, training, provision of supplies, enhanced community referral Cross-sectional The proportion of women accessing the hospital increased from 31 in 1990 to 98 in 1995, with a reduction in the case fatality rate from 32% to 5%. In addition, 444 abortion-related procedures were performed, compared with only 22 in 1990. Moderate
McGinn & Allen (2006) Guinea Camp Armed Conflict Early Recovery Refugee Reproductive health literacy programme Cross-sectional 50% of the survey respondents reported current use of modern contraceptives, while 24% reported using a condom the last time they had sex, of which both findings were interpreted as an increase since implementation of the reproductive health literacy programme. 92% of women who reported becoming pregnant since the reproductive health literacy programme reported attending at least three antenatal visits. High
Mullany et al. (2010) Myanmar Rural Armed Conflict Chronic IDP Training of community-based healthcare providers, antenatal, obstetric, and family planning service provision Cross-sectional Use of a modern method of contraception increased from 23.9% to 45.0% (prevalence rate ratio (PRR) 1.88, 95% CI 1.63, 2.17). Unmet family planning needs dropped from 61.7% to 40.5% (PRR 0.65, 95% CI 0.60, 0.72), while birth attendance by someone trained in emergency obstetric care increased from 5.1% to 48.7% (PRR 9.55, 95% CI 7.21, 12.64). High
Zaman et al. (2013) Pakistan Urban & Rural Natural Disaster Stabilised General Population Health system strengthening including strengthening management capacities of district health authorities, improving access to quality primary healthcare services, increasing participation of communities in health service management, and improving household level knowledge and care-seeking behaviours Cross-sectional Increases in the use of modern contraceptives (18% to 22%), at least one antenatal care visit (70.3% to 73.6%), and presence of a skilled birth attendant (36% to 38%) were non-significant. A statistically significant increase in receipt of postnatal care from 25% to 33.3% was reported (p<0.01). High