Table 2.

Percent of Responders on CGI as Reported by Patients and Physicians

	Per Protocol			Intent-To-Treat
Condition	Immediate	3 Month	6 Month	Immediate	3 Month	6 Month
Patient-Report CGI
MC-CBT	68.1% ± 8.1	64.0% ± 8.8	63.9% ± 8.8	61.0% ± 8.0	57.0% ± 8.4	56.6% ± 8.4
S-CBT	64.6% ± 8.9	64.6% ± 9.3	58.1% ± 9.4	54.5% ± 8.4	53.3% ± 8.6	48.1% ± 8.6
EDU	46.7% ± 8.8	49.5% ± 9.3	51.0% ± 9.6	43.5% ± 8.4	45.8% ± 9.0	47.0% ± 9.2
MC-CBT – S-CBT	3.5% ± 12.0	<1% ± 12.7	5.9% ± 12.9	6.5% ± 11.6	3.7% ± 12.0	8.5% ± 12.0
MC-CBT – EDU	21.5% ± 12.0**	14.5% ± 12.8*	12.9% ± 13.0a,b	17.6% ± 11.6**	11.2% ± 12.3a,b	9.6% ± 12.5
S-CBT – EDU	18.1% ± 12.5**	15.0% ± 13.1*	7.1% ± 13.4	11.1% ± 11.9a,b	7.5% ± 12.2	1.1% ± 12.6
MC-CBT – S-CBT CI	−8.5% to 15.5%	−13.2% to 12.5%	−7.0% to 18.7%	−5.1% to 18.0%	−8.3% to 15.8%	−3.6% to 20.5%
Physician-Rated CGI
MC-CBT	63.0% ± 9.0	-	66.4% ± 9.1	55.7% ± 8.6	-	58.4% ± 8.9
S-CBT	61.0% ± 9.4	-	64.0% ± 9.9	50.6% ± 8.7	-	51.6% ± 9.2
EDU	43.6% ± 9.2	-	49.6% ± 10.5	40.4% ± 8.8	-	44.8% ± 10.0
MC-CBT – S-CBT	2.0% ± 13.0	-	2.4% ± 13.5	5.1% ± 12.2	-	6.8% ± 12.8
MC-CBT – EDU	19.4% ± 12.9**	-	16.8% ± 13.9*	15.2% ± 12.3**	-	13.7% ± 13.4*
S-CBT – EDU	17.4% ± 13.1*	-	14.4% ± 14.5a,b	10.1% ± 12.4	-	6.8% ± 13.6
MC-CBT – S-CBT CI	−10.0% to 15.0%	-	−11.1% to 15.9%	−7.1% to 17.3%	-	−5.9% to 19.6 %

notes:

^*p < 0.05,

^**p < 0.01,

^ap < 0.08;

^btrend p value using listwise deletion is p < 0.05 for chained equation missing data algorithm; MC-CBT - S-CBT CI = 95% CI for difference; numbers after ± are margins of error (half widths of 95% CIs); IBSOS was not designed to collect blind ratings at 3 month follow up