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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Am J Transplant. 2018 Feb 14;18(7):1626–1635. doi: 10.1111/ajt.14650

Figure 2. Increased frequency of cells secreting SAg-specific T-cells.

Figure 2

(A) Recipient who received anti-MYO IgG on day 0 showed increased frequency of TNF-α, IFN-γ, and IL-17, as well as decreased frequency of IL-10-secreting CD4+ T-cells specific to MYO compared with a recipient who received anti-MYO IgG on day 7. (B) Recipient with administration of anti-MYO IgG on day 0 showed increased frequency of TNF-α, IFN-γ, and IL-17, as well as decreased frequency of IL-10-secreting CD4+ T-cells specific to VIM compared with recipient who received anti-MYO IgG on day 7. All data were normalized with normal mice data (results from normal mice subtracted from results obtained from transplant mice). Five animals/group.