Table 1.
Rabies virus neutralizing antibody titer (IU/mLb) | ||||||
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Animal no. | Titer groupa | Days from capture to challenge | At baselinec | At challengec | At 7 d postchallengec | Survivald |
125 | Negative | 105 | 0.01 | 0.01 | 0.01 | N |
5199 | Negative | 105 | 0.01 | 0.01 | 0.01 | N |
5142 | Negative | 107 | 0.01 | 0.01 | 0.01 | N |
5143 | Negative | 107 | 0.01 | 0.01 | 0.01 | N |
5162 | Negative | 107 | 0.01 | 0.01 | 0.01 | N |
5714 | Negative | 107 | 0.01 | 0.01 | 0.01 | N |
5038 | Negative | 151 | 0.01 | 0.01 | 0.01 | N |
5044 | Negative | 198 | 0.01 | 0.01 | 0.10 | N |
123 | Negative | 108 | 0.01 | 0.01 | 0.01 | N |
5198 | Low | 105 | 0.05 | 0.01 | 0.01 | N |
5716 | Low | 107 | 0.06 | 0.01 | 0.01 | N |
5718 | Low | 107 | 0.06 | 0.01 | 9.00 | Y |
5667 | Low | 86 | 0.08 | 0.01 | 0.68 | Y |
122 | Low | 108 | 0.07 | 0.01 | 0.01 | N |
5672 | Low | 129 | 0.08 | 0.01 | 0.07 | Y |
5745 | Low | 129 | 0.11 | 0.01 | 0.01 | Y |
5167 | Low | 151 | 0.11 | 0.01 | 0.01 | N |
5227 | Medium | 128 | 0.13 | 0.01 | 0.55 | Y |
5938 | Medium | 128 | 0.13 | 0.07 | 0.55 | Y |
5749 | Medium | 128 | 0.14 | 0.01 | 0.55 | Y |
5164 | Medium | 151 | 0.19 | 0.01 | 0.55 | N |
5459 | Medium | 152 | 0.22 | 0.01 | 0.07 | N |
5047 | Medium | 149 | 0.23 | 0.01 | 0.01 | N |
5160 | Medium | 151 | 0.36 | 0.01 | 0.10 | N |
5032 | Medium | 152 | 0.37 | 0.01 | 0.01 | N |
5195 | Medium | 149 | 0.43 | 0.10 | 0.13 | Y |
5043 | Medium | 149 | 0.40 | 0.13 | 0.05 | N |
5936 | High | 129 | 0.50 | 0.16 | 0.01 | Y |
5668 | High | 130 | 0.50 | 0.55 | 0.55 | Y |
4104 | High | 152 | 0.62 | 0.22 | 0.55 | Y |
5145 | High | 151 | 0.76 | 0.40 | 0.55 | Y |
5194 | High | 198 | 0.90 | 0.08 | 37.50 | Y |
5186 | High | 198 | 1.70 | 0.45 | 37.50 | Y |
5046 | High | 198 | 2.20 | 0.36 | 37.50 | Y |
5040 | High | 199 | 2.50 | 2.00 | 37.50 | Y |
5183 | High | 198 | 4.30 | 0.10 | 1.16 | Y |
5189 | High | 198 | 10.40 | 0.01 | 0.01 | N |
Group categories based on animal's rabies virus neutralizing antibody level at baseline: negative: <0.05 IU/mL, low: ≥0.05–0.11 IU/mL, medium: >0.11–<0.5 IU/mL, high: ≥0.5 IU/mL.
IU/mL = international units/milliliter.
Animal blood sampling time periods: baseline = day animal captured in the wild, challenge = day animal challenged with rabies virus.
Survival status of animals: Y= survived rabies challenge, N = developed signs consistent with rabies and was euthanized. All euthanized animals were confirmed rabid by direct fluorescent antibody.