Table 5.
Correlations between segmental glomerulosclerosis or adhesion and renal outcome at 6 months in the whole cohort: univariable and multivariable analysis
| Rate of renal function variation |
Risk of combined event: CKD stage 3 or 10% decline in eGFR n = 9 |
|||
|---|---|---|---|---|
| Univariable rate of renal function variation (ml/min per 1.73 m2) | Multivariablea (Linear least-squares fitting) |
Univariable odds ratio (95% CI) | ||
| Model A n = 68 β (SD) |
Model B n = 66 β (SD) |
|||
| S0 (n = 27) | 23.6 ± 31 | −9.9 (4.5) P = 0.029 |
−7.1 (4.8) P = 0.14 |
n = 8 −1.62 (−4.57 to 0.15) P = 0.14 |
| S1 (n = 49) | 8.3 ± 21.4 P = 0.015 |
|||
CI, confidence interval; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; S1 presence or S0 absence of segmental glomerulosclerosis or adhesion.
a
Model A: Multivariable with 2 pathological features + initial eGFR + initial proteinuria + age at diagnosis; Model B: Multivariable with 2 pathological features + initial eGFR + initial proteinuria + age at diagnosis, follow-up proteinuria and immunosuppressive treatment.