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. 2018 Feb 23;32(7):1598–1608. doi: 10.1038/s41375-018-0034-z

Fig. 4.

Fig. 4

Persisting pre-leukemic mutations and minimal residual disease. MRD levels were assessed a by qPCR in 46 NPM1-mutated patients and b by flow cytometry in 82 patients. Boxplots show the median, 25th/75th percentile, and minimum/maximum level of a NPM1mut/ABL1 ratio and b LAIP-positive cells, for patients with and without persisting mutations in the remission sample