Skip to main content
. 2018 Mar 30;3(4):926–938. doi: 10.1016/j.ekir.2018.03.015

Figure 4.

Figure 4

Association between mean fluorescence intensity (MFI)−donor-spectific antibody (DSA) and donor-specific antibody−C3d complement-binding (DSA-C3d) and flow cytometry crossmatch (FC-XM) positivity. (a) Comparison between mean MFI and DSA-C3d positivity (both class I and class II). (b) Comparison of MFI between either class I or class II DSA-C3d+ and DSA-C3d−. (c) Comparison between mean MFI-DSA and FC-XM positivity. (d) Receiver operating characteristic (ROC) curve analysis of MFI-DSA predicting DSA-C3d positivity. Mean MFI DSA-C3d– versus DSA-C3d+: 3799 ± 1773 versus 12,414 ± 5884, P < 0.001. Mean class I MFI DSA-C3d− versus DSA-C3d+ was 4259 ± 1612 versus 10,608 ± 7569, P = 0.026, respectively. Mean class II MFI DSA-C3d− versus DSA-C3d+ was 2801 ± 1629 versus 12,355 ± 5049, P < 0.001, respectively. Mean MFI-DSA in FC-XM− and FC-XM+ cases: 7619 ± 6358 versus 10,510 ± 6130, P = 0.21. Area under the curve (AUC): 0.838, 95% confidence interval (CI) = 0.65−1.00, P = 0.008.