. 2018 Mar 16;3(4):879–888. doi: 10.1016/j.ekir.2018.03.005

Table 3.

Odds ratios (95% CI) for risk of rapid eGFR_cysC decline (>3 ml/min per 1.73 m² per year) in 2426 post–myocardial infarction patients, for different cardiovascular risk factors

Risk factor^a	Crude	Model 1	Model 2
Diabetes	1.77 (1.41–2.21)^b	1.79 (1.43–2.25)^b	1.72 (1.36–2.17)^b
High blood pressure	1.48 (1.22–1.79)^b	1.41 (1.17–1.72)^b	1.43 (1.18–1.74)^b
High LDL	0.81 (0.67–0.98)^c	0.82 (0.68–0.99)^c	0.80 (0.66–0.98)^c
Current cigarette smoking	1.13 (0.88–1.45)	1.23 (0.95–1.58)	1.21 (0.94–1.57)
Obesity	1.09 (0.88–1.36)	1.17 (0.93–1.46)	1.15 (0.92–1.45)

CI, confidence interval; eGFR_cysC, glomerular filtration rate estimated by serum cystatin C; LDL, low–density lipoprotein.

Diabetes was defined as self–reported diagnosis by a physician, use of glucose–lowering drugs, or hyperglycemia. High blood pressure was defined as systolic blood pressure of ≥140 mm Hg and/or diastolic blood pressure of ≥90 mm Hg, irrespective of use of blood pressure lowering drugs. High LDL was defined as serum LDL level of ≥2.5 mmol/l. Obesity was defined as BMI of ≥30.0 kg/m². Model 1: adjusted for age, sex, and treatment group. Model 2: model 1 plus additional adjustment for current smoking, alcohol consumption, level of education, diabetes, high blood pressure, high LDL, and obesity. Analyses for obesity were not adjusted for diabetes, high blood pressure, and high LDL.

Reference: absence of the risk factor of interest.

P < 0.001.

P < 0.05.