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. 2018 Jul 6;8:10240. doi: 10.1038/s41598-018-28551-2

Figure 8.

Figure 8

Effect of RAD288 and RAD289 on 3D mOECs spheroids. (a) Representative images of mOECs spheroids after drug exposure. Scale bar = 100 µm. (b) Cell viability of mOECs spheroids exposed to 0.2% DMSO (Control), 1% G5 supplement and RAD288 (0.78–6.25 µM) using the resazurin metabolic activity indicator. (c) Cell viability of mOECs spheroids exposed to 0.2% dimethyl sulfoxide (Control), 1% G5 Supplement and RAD289 (0.78–6.25 µM) using the resazurin metabolic activity indicator. Triplicate wells were used in three separate experiments, mean ± SEM, ***p < 0.001, **p < 0.01, Student’s t-test.