Figure 1.

XP-CLR Scan to Detect Positive Selection in the PGR Locus

The peaks indicate signatures of positive selection that has differentiated the multi-locus allele frequency spectrum in one population from the other. Comparisons were performed for CHB-CEU, CHB-YRI, and CEU-YRI. Significance was empirically determined by the upper 5% XP-CLR scores across the entire genome for each comparison (the gray horizontal line). XP-CLR scan was performed with a maximum window of 0.1 cM.