Table 2.

Study characteristics in determining risk factor supporting evidence.

Probable risk factors requirements	Possible risk factor	Unlikely risk factor or more research needed
Number of studies ≥5	Number of studies ≥ 5	Number of studies ≤5
Number of patients ≥1500	Number of patients ≥2000	Number of patients ≤2000
Percent of patients in studies identified as positive for risk factor ≥70%	Percent of patients in studies identified as positive for risk factor ≥60% OR	Percent of patients in studies identified as positive for risk factor <60%
Percent of studies identified as positive for risk factor ≥70%	Percent of studies identified as positive for risk factor ≥60%	Percent of studies identified as positive for risk factor <60%