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. 2018 Jul 7;7(6):388–396. doi: 10.1302/2046-3758.76.BJR-2018-0037

Table II.

NTH aseptic lymphocyte-dominated vasculitis-associated lesion (ALVAL) grading system. The development of the grading system, interobserver reliability scores and comparison with other grading systems are described in the supplementary material

Grade 0: ALVAL absent Grade 1: Mild ALVAL Grade 2: Moderate ALVAL Grade 3: Severe ALVAL
Vascular cuffs None Yes Large perivascular lymphocytic aggregates Large confluent lymphocytic aggregates
Synovial membrane Intact Grade 0 or 1 Grade 2 or 3 Grade 4
Hyalinization No No Can be present Present
Germinal centres No No Can be present Present