Table 1.

Summary of meta-regression analysis using dosage and duration as covariates on appropriate cardiometabolic biomarkers (i.e. ≥ 10 RCTs)

Moderator variable	p value	Meta-regression of moderator variable vs. effect size
Low density lipoprotein
Duration	0.85	Slope 0.00, 95% CI − 0.01 to 0.01, df = 27
Dosage	0.14	Slope 0.03, 95% CI − 0.01 to 0.07, df = 27
Triglycerides
Duration	0.35	Slope 0.01, 95% CI − 0.01 to 0.01, df = 31
Dosage	0.87	Slope -0.00, 95% CI − 0.07 to 0.08, df = 31
Glycated haemoglobin
Duration	0.11	Slope 0.01, 95% CI − 0.00 to 0.02, df = 32
Dosage	0.55	Slope 0.03, 95% CI − 0.07 to 0.13, df = 32