Table 4.
Final parsimonious models predicting recurrence of depression
| Primary Model (N=214) | Secondary Model (N=182) | |||||
|---|---|---|---|---|---|---|
| Variable | Hazard Ratio | Wald X2 | p value | Hazard Ratio | Wald X2 | p value |
| Age | 1.032 (0.999 – 1.067) | 3.54 | 0.0599 | 1.030 (0.994–1.068) | 2.66 | 0.1026 |
| Sex | 1.536 (1.027 – 2.297) | 4.38 | 0.0365 | 1.457 (0.941 – 2.257) | 2.84 | 0.0919 |
| Age of Onset | 0.990 (0.981 – 0.999) | 4.66 | 0.0310 | 1.000 (0.988 – 1.013) | 0.01 | 0.9742 |
| CESD Item 18, baseline (felt sad) | 1.302 (1.080 – 1.569) | 7.66 | 0.0056 | 1.357 (1.108 – 1.663) | 8.69 | 0.0032 |
| MADRS Item 10, baseline (suicidal thoughts) | 1.175 (1.002 – 1.377) | 3.96 | 0.0466 | 1.131 (0.952 – 1.344) | 1.97 | 0.1610 |
| MADRS total, pre-censoring score | 1.081 (1.033 – 1.131) | 11.42 | 0.0007 | 1.081 (1.030 – 1.134) | 9.86 | 0.0017 |
| Perceived stress severity | 1.121 (1.022 – 1.229) | 5.84 | 0.0157 | 1.125 (1.109 – 1.243) | 5.42 | 0.0199 |
| IADL | 1.060 (1.005 – 1.119) | 4.56 | 0.0327 | 1.061 (1.003 – 1.123) | 4.24 | 0.0394 |
| Instrumental Social Support | 0.885 (0.812 – 0.963) | 7.98 | 0.0047 | 0.846 (0.766 – 0.934) | 10.94 | 0.0009 |
| More than 3 prior depressive episodes | - | - | - | 2.107 (1.252 – 3.548) | 7.87 | 0.0050 |
Data presented as Hazard Ratio (95% Confidence Interval). CESD = Center for Epidemiological Studies – Depression Scale; IADL = Instrumental Activities of Daily Living; MADRS = Montgomery-Asberg Depression Rating Scale.