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. 2018 Jul 7;15:201. doi: 10.1186/s12974-018-1227-0

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Quantification of CD11B+ and CD45+ cells in ventral ON vulnerable to secondary degeneration. Mean ± SEM numbers of a CD45+ and c CD11b+ cells in control, uninjured optic nerve and at 3, 7, and 28 days following partial optic nerve transection, in ventral optic nerve vulnerable to secondary degeneration are shown. * indicates significantly different from normal (p ≤ 0.05), n = 6/group. Representative low- and high-magnification images of b CD45 and d CD11b in the ventral aspect of the optic nerve are shown in control uninjured, 3, 7, and 28 days after injury. Examples of CD45+ and CD11b+ cells, boxed cells at low magnification, are shown in high magnification. Scale bar of b and d: 20 μm top images and 3 μm bottom images for each