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. 2018 Jun 14;5(7):300–326. doi: 10.15698/mic2018.07.638

Table 1.

Overview of in vivo models for assessing efficacy of antifungal drugs or treatments [references]..

Animal species Type of infection Candida sp. Aspergillus sp. Cryptococcus sp. Other fungi
Galleria melonella (greater wax moth) 127,128,129,130,131,132,133,134,135,136,137,138,139 133,140,141,142,143,144 145,146,147,148,149 150,151,152,153,154,155
Bombyx mori (silkworm) 156 157 158,159,160
Caenorhabditis elegans 100,136,161,162,163,164,165,166,167,168,169,170,171,172,173 166,174,175 176
Drosophila melanogaster 177,178 179 180
Danio rerio Zebrafish larvae 165 145 181,182
Mice systemic 183,184,185,186,187,188 189 190 191,192
Mice oropharyngeal 184,193,194,195,196,197
Mice vaginal 198,199,200,201,202
Mice Biofilm, including dentures/keratitis 203,204,205,206,207,208
Mice intratracheal/lung/ central nervous system 209,210,211,212,213 147,214,215,216,217 218
Mice Cutaneous 219 220 180
Rats Biofilm 93,101,221,222,223,224,225,226
Guinea pigs 227 228,229 230 231