Table 3.
Variable | Early recurrence (<3 yr) (n = 71) | Late recurrence (≥3 yr) (n = 27) | Univariate analysis (P value) | Multivariate analysis (OR, 95% CI, P value) |
---|---|---|---|---|
Age (yr) | 0.382 | |||
<70 | 56 (78.9%) | 24 (88.9%) | ||
≥70 | 15 (21.1%) | 3 (11.1%) | 0.726 (0.174–3.024) 0.660 | |
Gender | 0.473 | |||
Male | 39 (54.9%) | 17 (63.0%) | 0.996 (0.361–2.747) 0.993 | |
Female | 32 (45.1%) | 10 (37.0%) | ||
Tumor location | 1.000 | |||
Right colon | 18 (25.3%) | 7 (25.9%) | ||
Left colon | 12 (16.9%) | 4 (14.8%) | ||
Rectum | 41 (57.7%) | 16 (59.3%) | ||
Tumor size | 0.965 | |||
<5 cm | 24 (33.8%) | 9 (33.3%) | ||
≥5 cm | 47 (66.2%) | 18 (66.7%) | ||
Gross type | 0.280 | |||
Fungating | 30 (42.3%) | 14 (51.9%) | ||
Infiltrative | 36 (50.7%) | 10 (37.0%) | ||
Unknown | 5 (7.0%) | 3 (11.1%) | ||
Cell type | 0.614 | |||
Nonmucinous | 68 (95.8%) | 25 (92.6%) | ||
Mucinous | 3 (4.2%) | 2 (7.4%) | ||
Differentiation | 0.818 | |||
WD | 3 (4.2%) | 1 (3.7%) | ||
MD | 53 (74.6%) | 22 (81.5%) | ||
PD | 15 (21.1%) | 4 (14.8%) | ||
Lymphatic invasion | 0.012 | |||
Absent | 10 (14.1%) | 10 (37.0%) | ||
Present | 61 (85.9%) | 17 (63.0%) | 0.309 (0.103–0.924) 0.036 | |
Vascular invasion | 1.000 | |||
Absent | 71 (100%) | 27 (100%) | ||
Present | 0 (0%) | 0 (0%) | ||
T category | 0.193 | |||
T1 | 0 (0%) | 0 (0%) | ||
T2 | 1 (1.4%) | 2 (7.4%) | ||
T3 | 67 (94.4%) | 25 (92.6%) | ||
T4 | 3 (4.2%) | 0 (0%) | ||
N category | 0.102 | |||
N0 | 12 (16.9%) | 10 (37.0%) | ||
N1 | 21 (29.6%) | 6 (22.3%) | ||
N2 | 38 (53.5%) | 11 (40.7%) | ||
Stage | 0.051 | |||
I | 0 (0%) | 1 (3.7%) | ||
II | 13 (18.3%) | 9 (33.3%) | ||
III | 58 (81.7%) | 17 (63.0%) | 1.315 (0.256–6.753) 0.743 | |
COX-2 expression | 0.001 | |||
Negative | 45 (63.4%) | 7 (25.9%) | ||
Positive | 26 (36.6%) | 20 (74.1%) | 4.656 (1.696–12.779) 0.003 |