Table 8.
Effect of the ethyl acetate flowers extract of Anthyllis henoniana on oxidative stress markers of different experimental groups of rats.
| Groups | SOD (U/mg protein) | CAT (umole H2O2/min/mg protein) | GSH (ug/mg protein) | TBARS (nmol MDA/mg protein) | AOPP (nmol/mg protein) |
|---|---|---|---|---|---|
| Liver | |||||
| Cont | 70.12±1.30 | 1.70±1.32 | 40.12±1.25 | 11.00±0.25 | 0.16±1.25 |
| Diab | 60.01 ±1.20∗ | 0.80±0.02 | 12.3±0.02∗∗∗ | 28.50±1.21∗∗∗ | 0.67±1.05∗∗∗ |
| Diab+ EAEx | 64.55±7.39# | 1.44±2.24### | 27.07±1.9###@@@ | 16.38±9.36###@@ | 0.52±0.30### |
| Diab+ Acar | 50.22± 1.39### | 1.5±0.02## | 30.00±0.4### | 14.47±6.13### | 0.32±0.02### |
| Rein | |||||
| Cont | 36.59±5.70 | 1.25±0.44 | 17.85±3.97 | 20.12±1.03 | 0.11±1.56 |
| Diab | 18.24±1.70∗∗∗ | 0.11±0.82∗∗∗ | 9.06±1.19∗∗∗ | 24.00±0.23∗∗∗ | 0.30±1.231∗∗∗ |
| Diab+ EAEx | 30.16±0.03###@@@ | 0.40±0.83##@ | 13.12 ±5.06###@ | 19.81±5.38###@ | 0.15±0.08###@@ |
| Diab+ Acar | 20.36±2.36###@@@ | 0.79±0.12### | 19.00±0.17## | 18.31±1.50### | 0.17±0.25### |
| Pancreas | |||||
| Cont | 97.71±1.58 | 1.05±0.14 | 7.17±0.13 | 10.00±0.75 | 0.24±0.12 |
| Diab | 39.62±2.23∗∗∗ | 0.10±1.02∗∗∗ | 3.21±0.02∗∗∗ | 25.81±1.70∗∗∗ | 0.87±0.14∗∗∗ |
| Diab+ EAEx | 53.63±1.06###@@@ | 2.89±1.12### | 8.50±6.10### | 10.37±3.19### | 0.33±0.13### |
| Diab+Acar | 65.15±4.92### | 0.81±1.12### | 2.53±1.00### | 12.71±1.73### | 0.25±0.23###@@@ |
Values represent means ± SD (n = 8 for each group). Control groups (Cont) and diabetic control (Diab). Diab+ EAEx: diabetic rats treated with EAEx of Anthyllis henoniana at 400 mg/kg bw per day for 28 days; Diab+Acar: diabetic rats treated with acarbose at dose of 12 mg/kg bw per day for 28 days. Values differ significantly at∗p<0.05 and ∗∗∗p < 0.001, as considered significant compared to control groups;#p<0.05## and p<0.01,###p < 0.001, as considered significant compared with diabetic rats; @p<0.05, @@p<0.01, and @@@p < 0.001, as considered significant compared with diabetic rats treated with acarbose.