Table 1.
Demographic and clinical characteristics of study participants.
| Parameters | AIH patients | HCs |
|---|---|---|
| Number | 30 | 20 |
| Age (years) | 49 (38–76) | 51 (41–74) |
| Gender: female/male | 22/8 | 14/6 |
| ALT (U/L) | 126.4 ± 111.9∗ | 27.2 ± 8.2 |
| AST (U/L) | 102.4 ± 55.3∗ | 22.7 ± 5.7 |
| γ-GT (U/L) | 88.9 ± 31.4∗ | 25.1 ± 7.4 |
| ALP (U/L) | 132.6 ± 36.8∗ | 89.5 ± 23.6 |
| Anti-ANA(+) | 23/30 (76.7%)∗ | 0/20 (0%) |
| Anti-ANA titer | 1 : 640 (1 : 80–1 : 10000) | — |
| Anti-SMA(+) | 2/30 (6.7%)∗ | 0/20 (0%) |
| Anti-SMA titer | 1 : 1000 (1 : 160–1 : 3200) | — |
| IgG (g/L) | 15.8 ± 3.8∗ | 7.8 ± 2.3 |
| IgM (g/L) | 6.8 ± 1.9∗ | 2.64 ± 0.87 |
| IgA (g/L) | 3.98 ± 2.2∗ | 1.6 ± 1.1 |
| WBC count (∗109/L) | 7.62 (5.6–11.2)∗ | 5.08 (3.9–9.2) |
Data shown are expressed as mean ± SD. Normal values: ALT: <40 IU/L; AST: <40 IU/L; ANA: <1 : 80; SNA: <1 : 80. IgG: normal range = 7–16 g/L; IgM: normal range = 0.7–4.6 g/L; IgA: normal range = 0.4–2.3 g/L. HC: healthy control; AIH: autoimmune hepatitis. ∗P < 0.05 versus HC.