Fig. 5.

Analysis of day 2 serum and tissue viral titers in RVFV-infected hamsters treated with galidesivir (efficacy experiment 2). Hamsters were treated as described in Table 3 and Fig. 4. Four animals per group were designated for sacrifice on day 2 p.i. for analysis of A) serum, B) liver, C) spleen, and D) brain virus titers. Unique symbols in each treatment group represent values for the same animal across all parameters. The x-axis represents the lower limit of detection and the grey-hashed lines indicate the assay upper limits of detection. ***P < 0.001 compared to animals receiving placebo.