Table 3.
Significant Association of HLA-A alleles and B~C haplotypes with Multiple Sclerosis
Locus | Allele | Controls (N) | Patients (N) | OR | 95% CI Lower | 95% CI Upper | p-value | Significance 1 |
---|---|---|---|---|---|---|---|---|
A | 02:01 | 223 | 164 | 0.69 | 0.54 | 0.87 | 0.0014642 | * |
A | 03:01 | 114 | 141 | 1.32 | 1 | 1.74 | 0.0427 | * |
A | 30:02 | 5 | 16 | 3.32 | 1.15 | 11.62 | 0.013665 | * |
A | 33:01 | 11 | 3 | 0.28 | 0.05 | 1.05 | 0.035161 | * |
C~B | 03:04~40:01 | 50 | 14 | 0.27 | 0.14 | 0.51 | 6.7591Eā06 | * |
C~B | 05:01~44:02 | 57 | 37 | 0.65 | 0.41 | 1.01 | 0.043834 | * |
C~B | 07:01~08:01 | 76 | 101 | 1.41 | 1.02 | 1.96 | 0.032259 | * |
C~B | 07:02~07:02 | 91 | 160 | 1.99 | 1.5 | 2.66 | 8.8881Eā07 | * |
C~B | 12:03~18:01 | 12 | 24 | 2.08 | 0.99 | 4.59 | 0.036793 | * |
Details of each comparison are included in the legend to Table 2.