Table 2.
Possible beneficial effect of plants against Cd-induced kidney toxicity.
Plant Name | Effect of Cd on kidney | Outcome | References |
---|---|---|---|
Quercetin | Decreases enzymatic antioxidants activity and non-enzymatic status, Decreases kidney function, increases LPO, tubular necrosis, degeneration, dilation, desquamation, thickening of basement membrane and luminal cast formation |
Attenuates alteration considering all premises | [48] |
Lactobacillus plantarum CCFM8610 |
Perturbation of Ca, Fe, Mn, Zn concentration Increases MDA, decreases CAT, SOD, GPx acivity and GSH level. Cloudy swelling and necrosis of tubules and dilation of glomeruli. |
Normalizes the pathological condition through oral route rather IP administration | [49] |
Flax seed oil (Linum usitatissimum) | Decreases antioxidant activity, increases NO level, MDA | Normalizes the pathological condition | [51] |
Curcumin Curcuma longa L | No observation | Decreases hepatic LPO, increases CAT, GPX activity, GSH level | [52] |
Resveratrol (3,5,4-trihydroxystilbene) | |||
melatonin | |||
Naringenin | Increases serum urea, uric acid, creatinine level, increases LPO, carbonyl compound, hydroperoxides, Decreases non-enzymatic and enzymatic antioxidant status. necrosis and cloudy swelling of tubules, inflammatory cell infiltration, tubular necrosis, desquamation and degeneration of glomeruli and renal tubules |
Normalizes the pathological condition | [53] |