Fig. 2.

Effects of supplementation with an AC-rich extract on GTT and ITT responses in HFD-fed rats. GTT (A) and ITT (B) were performed on weeks 9 and 11 on the diets, respectively. Mice were fed a control diet (empty triangles, empty bars), the control diet supplemented with 40 mg AC/kg body weight (full triangles, dashed bars), a HFD (black circles, black bars), or the HFD supplemented with 2 (light pink diamonds, light pink bars), 20 (dark pink diamonds, dark pink bars), or 40 mg AC/kg body weight (red circles, red bars). The area under the curve for GTT and ITT tests were calculated, values referred to the control group, and shown as bars in the right panels. Results are shown as means ± SE and are the average of 9–10 animals/group. Values having different superscripts are significantly different (p < 0.05, one-way ANOVA).