Perfusate inflammatory mediators and secretary phospholipase A2 (sPLA2) levels. EVLP perfusate (A) inflammatory mediators interleukins and (B) secretary phospholipase A2 levels at 6 hours were reduced by lung lavage and surfactant replacement. EVLP, ex vivo lung perfusion; PVR, pulmonary vascular resistance; SF, surfactant. *, P<0.05; †, P=0.0245.