Table 2. Lysophosphatidylcholine in bronchoalveolar fluid.
Variables | Control (mean ± SD) | Lavage (mean ± SD) | Surfactant (mean ± SD) | Lavage+ surfactant (mean ± SD) | P value |
---|---|---|---|---|---|
Total PC (ng/kg body weight) | 5,714±4,122 | 4,640±1,929 | 11,772±9,260 | 7,497±4,521 | 0.2800 |
PC 30/0 | 375.5±258.6 | 257.5±108.0 | 1,460.3±1,373.6 | 798.6±521.7 | 0.0400 |
PC 32/0 | 2,723.8±1,973.2 | 2,309.8±953.4 | 4,817.6±3,258.1 | 3,090.9±1,682.2 | 0.3900 |
PC 34/0 | 283.7±228.6 | 217.4±110.8 | 546.1±420.4 | 416.6±263.2 | 0.2800 |
PC 34/1 | 1,002.1±740.2 | 752.0±266.4 | 2,752.6±2,488.0 | 1,808.0±1,179.9 | 0.1100 |
PC 34/2 | 652.2±479.3 | 544.5±261.4 | 1,237.9±987.9 | 699.0±466.8 | 0.5400 |
PC 36/1 | 113.5±67.6 | 96.1±56.7 | 284.4±275.5 | 227.7±157.0 | 0.2600 |
PC 36/2 | 271.9±184.9 | 241.2±141.6 | 415.2±314.7 | 279.3±149.8 | 0.7900 |
PC 36/4 | 126.2±125.9 | 85.8±44.5 | 141.3±110.9 | 78.5±56.8 | 0.6600 |
PC 38/4 | 116.1±84.5 | 102.5±57.4 | 103.0±69.8 | 71.6±48.4 | 0.7000 |
PC 38/6 | 37.8±38.0 | 23.8±11.5 | 32.0±22.8 | 20.8±14.8 | 0.6300 |
PC 40/6 | 11.4±7.2 | 9.1±3.6 | 8.0±4.1 | 6.1±3.7 | 0.3400 |
Total LPC (ng/kg body weight) | 12.07±7.70 | 11.88±7.11 | 18.73±11.87 | 7.49±4.85* | 0.1500 |
LPC 16:0 | 7.57±4.66 | 8.04±5.07 | 12.31±7.90 | 4.80±3.20 | 0.1700 |
LPC 18:0 | 2.26±1.36 | 1.84±0.89 | 3.67±2.85 | 1.58±1.10 | 0.3700 |
LPC 18:1 | 2.24±1.75 | 2.00±1.30 | 2.76±1.73 | 1.11±0.57 | 0.3900 |
Total PC/LPC | 585±287 | 505±274 | 675±369 | 1009±143 | 0.0438 |
*, P=0.0317 vs. surfactant group by Mann-Whitney test. LPC, lysophosphatidylcholine; PC, phosphatidylcholine; SD, standard deviation; PC 30/0, PC 16:0/14:0 and PC 14:0/16:0; PC 32/0, PC 16:0/16:0, PC 14:0/18:0 and PC 18:0/14:0; PC 34/0, PC 16:0/18:0 and PC 18:0/16:0; PC 34/1, PC 16:0/18:1; PC 34/2, PC 16:0/18:2; PC 36/1, PC 18:0/18:1 and PC 18:1/18:0; PC 36/2, PC 18:0/18:2; PC 36/4: PC 16:0/20:4; PC 38/4, PC 18:0/20:4; PC 38/6, PC 16:0/22:6; PC 40/6, PC 18:0/20:6.