Table 2. Characteristics of included studies.
| Author/Year | Country | Population | Mean age (year) | Sample size (%, female) | Source of infection | APACHE | Timing of initiating PMX | Duration of each PMX session (h) | No. of PMX sessions |
|---|---|---|---|---|---|---|---|---|---|
| Nakamura/1999 | Japan | Septic shock | 53.8 | 50 [40] | Miscellaneous | 24.8 | 6th day | 2 | 2 |
| Nemoto/2001 | Japan | Severe sepsis/septic shock | 61.9 | 98 (38.8) | Miscellaneous | 22.4 | 1st day | 4 | 1 or 2 |
| Suzuki/2002 | Japan | Septic shock | 64.5 | 48 (36.1) | Miscellaneous | 25 | 1st day | 4 | 1 |
| Vincent/2005 | Belgium, UK, Germany, The Netherlands, Spain, Japan | Severe sepsis/septic shock | 57.6 | 35 (37.1) | Abdominal | 17.7 | 1st day | 2 | 1 |
| Cruz/2009 | Italy | Severe sepsis/septic shock | 63.8 | 64 (34.4) | Abdominal | 20.5 | 1st day | 2 | 2 |
| Payen/2015 | France | Septic shock | 72 | 232 (42.2) | Abdominal | NR | 1st day | 2 | 2 |
| Srisawat/2016 | Thailand | Severe sepsis/septic shock | 68 | 59 (NR) | Miscellaneous | NR | 1st day | 2 | 2 |
NR, not reported; PMX, polymyxin B hemoperfusion; APACHE, Acute Physiology and Chronic Health Evaluation.