Table 5. Sensitivity analysis of mortality by risk of bias and industry sponsorship.
Risk of bias | No. of trials | Total sample size | Risk ratio (95% CI) | Heterogeneity | |||
---|---|---|---|---|---|---|---|
Q | df | I2, % | P value for I2 | ||||
Low risk in sequence generation | 3 | 331 | 0.98 (0.54–1.77) | 4.89 | 2 | 59.1 | 0.087 |
Low risk in allocation concealment | 3 | 331 | 0.98 (0.54–1.77) | 4.89 | 2 | 59.1 | 0.087 |
Low risk in blinding of outcome assessors | 2 | 296 | 0.95 (0.41–2.19) | 4.88 | 1 | 79.5 | 0.027 |
Low risk in incomplete outcome reporting | 4 | 390 | 1.05 (0.71–1.53) | 5.10 | 3 | 41.1 | 0.165 |
Presence of industry sponsorship | 2 | 296 | 0.95 (0.41–2.19) | 4.88 | 1 | 79.5 | 0.027 |