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. 2018 May 22;15(8):832–839. doi: 10.7150/ijms.23270

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PSN-A augments doxorubicin toxicity in prostate cancer cells. (A) LNCaP and DU145 cells were treated with PSN-A (25nM) and doxorubicin (2µM) either as a single agent or in combination for 24 h as indicated and apoptotic cell death was determined by flow cytometry. (B) Statistical analysis from A. Columns with different superscript letters differ significantly (P<0.05). (C) LNCaP and DU145 cells were treated with PSN-A and doxorubicin as single agent or in combination for 24 h as indicated. Total cell lysates were extracted and subjected to Western blot for the expression of cleaved PARP.