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. 2018 May 22;15(8):782–787. doi: 10.7150/ijms.24755

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HBOT in liver diseases. In liver, immediate HBOT reduces inflammation and oxidant stress to protect hepatocytes in liver injury. HBOT also facilitates hepatocyte proliferation and improves fibrogenesis. HBOT inhibits bacterial translocation to attenuate sepsis-induced liver injury. In addition, HBOT is definitely an effective therapy for artery thrombosis. Even though the role of HBO in liver cancer cell proliferation is undetermined, combination of HBOT and radiotherapy or chemotherapy sensitive cancer cells to death. However, improper HBOT leads to increase of oxidant stress and hepatotoxicity.