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. 2018 May 22;15(8):748–757. doi: 10.7150/ijms.24605

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Histological findings at POD 28. Bone marrow-like tissue was observed inside newly formed bone tissue surrounded by osteoblasts (arrowheads) and osteoclast-like cells (arrows). In the IBM area, bone tissue formation was detected around IBM, and bone marrow-like tissue formation (asterisks) occurred with adipocytes and hemocytes present. Blood cells of formed bone marrow-like tissue and osteoclasts-like cells surrounding neonatal bone were GFP-positive, whereas osteoblasts arrayed on the surface of formed bone tissue and osteocytes in neonatal bone were GFP-negative. Scale bars = 200 μm in magnification 100× and scale bars = 50 μm in magnification 400×.