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. 2018 Jun 13;15(9):953–960. doi: 10.7150/ijms.24146

Figure 1.

Figure 1

Effects of MA and EA on GNTI-induced scratching behavior. (A) MA or EA was applied to LI4 and LI11 acupoints 30 min before GNTI administration (0.3 mg/kg, s.c.) to the back of the neck. The number of scratching bouts was counted for 40 min after GNTI injection. Both MA and EA at LI4 and LI11 significantly attenuated GNTI-induced scratching behavior compared with scratching in the control group. Between-group comparisons for each group were performed by ANOVA, followed by the Dunnett's test (*P < 0.05; the GNTI-only group served as the reference group). MA at non-acupoints had no effect upon scratching. (B) MA or EA was applied to bilateral ST36 acupoints 20 min before GNTI administration. The mean number of scratching bouts was counted for 40 min after GNTI injection. Neither MA nor EA at ST-36 reduced scratching behavior. NAP = Non-acupoint.