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. 2018 May 26;15(9):859–866. doi: 10.7150/ijms.24928

Fig 2.

Fig 2

The myokine expression levels in osteosarcoma tissues compared with cancellous bone tissues. (A) Expression levels of myokine related with immunological regulation and inflammatory, CCL7, CHI3L1, CX3CL1, DDP4, IL1b, IL4, IL8, IL15, LIF and MCP1 showed significant differences. (B) Expression levels of myokines related with cell survival and differentiation, DCD, FGF2 and OSM showed significant differences. (C) Expression levels of myokines related with neural growth, BDNF showed significant differences. (D) Expression levels of myokines related with metabolism, ANGPTL4, Fam132b and FGF21 showed significant differences. (E) Myokines with other functions, TNF-α showed significant differences. (n = 8, **P < 0.01, *P < 0.05) (F) The protein level of ANGPTL4, IL15 and MCP1 in three randomly chosen OS tissues and cancellous bone tissues.