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. 2018 Feb 7;26(5):739–753. doi: 10.1016/j.jsps.2018.02.015

Table 1.

Contributions and advancements offered through the natural products chemistry discipline.

Drug discovery & development, semi-synthetics Drugs and other medicaments started with herbal origins, majority of drugs herbals before advent of synthetic drugs, feasible and cost-effective approach to drugs of semi-synthetic origin, contemporarily ∼50% drugs of natural origins, new templates in drug design and new chemical entities being continuously discovered



Chemical synthesis Retro-approach to biogenetic synthesis, total synthesis in a bio-mimetic pattern, new routes, new templates, and challenging molecular frameworks availability



Therapeutic agents Taxol, Cephalosporins, Penicillins, Tetracyclines, Camptothecin, Etoposides, Podophyllotoxin, Combretastatin, Homoharringtonine analogs, Marine-sourced Bryostatins, Ecteinascidin, Kahalalide F, etc.



Bioactives Insect-repellents, herbicides, natural pesticides, larvicidal, auxins, phytoalexins, antihelminth, anti-filarial, neuro-active, cardiovascular, anti-hyperlipidemic, liver-protective, anti-inflammatory, anti-microbial, anti-cancers, anti-oxidants, anti-diabetics, pain-killers, anti-spasmodics, digestives, purgative, anti-ulcers, aphrodisiacs, tonics, anti-allergens, etc.



Economics Developing world economy, economic up gradation in plant resource-rich nations, global imports, in-house native consumption, forest-economies, long-lasting sustenance, etc.



Pharmacopoeias, medical treatise, and alternative medicines Ayurveda, Unani (Greco-Arab-Indian), Chinese as major plant-based healing systems, African, Shaman, Red-Indian and other ethnobotanical medicinal usage traditions and treatise. Aromatherapy, Homeopathy, and Siddha systems of medicinal usage



Consumables Plant Pigments, Dyes, Essential oils, Fatty Acids & Lipids, Raisins and Gum, Aromatics, Alkaloids and Tannins, Neutraceuticals, Spices, Condiments, etc.



Plant-based drugs of abuse Hallucinogens, Narcotics, Cannabis, Opium, Semi-synthetics derivatives thereof



Technical products, fibers, and plant polymers Jute fibers, Paper, Paper-boards, etc., Pectins, Alginates, Cellulose, Marine-Sourced Products, etc.