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Knockdown of miR-21 activates PDCD4/NF-κB pathway in vitro. The effect of miR-21 on activation of PDCD4/NF-κB pathway was assessed in HR cultured HK-2 cells. (A–C) Expressions of PDCD4 and NF-κB were increased in the HK-2 cells challenged by HR and knockdown of miR-21 aggravated this effect. *P < 0.05, *** < 0.001, compared with Normoxia; #P < 0.051, ###P < 0.001, compared with Anti-scramble + HR, n = 6.
