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. 2018 Jun 26;9:1358. doi: 10.3389/fmicb.2018.01358

FIGURE 1.

FIGURE 1

Effects of SAV4189 on avermectin production and growth in Streptomyces avermitilis. (A) Organization of sav_4189 and its adjacent genes. (B) Avermectin yield in WT, sav_4189 deletion mutant (D4189), complemented strain (C4189), and overexpression strain (O4189) cultured in FM-I. Avermectin yield contains total yield of all eight components A1a, A1b, A2a, A2b, B1a, B1b, B2a, and B2b. NS, not significant; ∗∗P< 0.01 (comparison with WT by Student’s t-test). (C) Growth curves of WT, D4189, and O4189 cultured in FM-II. In this and subsequent figures, error bars represent SD of three replicates.