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. 2018 Jun 26;9:1358. doi: 10.3389/fmicb.2018.01358

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Copyright © 2018 Guo, Zhang, Lu, Liu, Chen, Li, Deng and Wen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcriptional analysis of aveR, sav_4189, and sav_4190 by qRT-PCR. (A) Transcriptional profile of sav_4189 during the avermectin fermentation process in WT grown in FM-I. Value of sav_4189 on day 1 was defined as 1. (B) aveR, (C) sav_4189, and (D) sav_4190 transcription levels in WT, D4189, and O4189 grown in FM-I. Value of each gene was calculated relative to WT value on day 2, defined as 1. sav_4189: 91-bp transcript amplified from remainder sav_4189 ORF in D4189 with primers ZX9 and ZX10. ^∗P< 0.05, ^∗∗P< 0.01, ^∗∗∗P< 0.001.