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Avermectin yield in various S. avermitilis strains grown in FM-I for 10 days. (A) WT and sav_4190 deletion mutant strains D4190-1, -2, and -3. (B) Industrial strain A-144 and its derivatives (O4189/A-144: sav_4189 overexpression strain; D4190/A-144: sav_4190 deletion strain). ∗∗P< 0.01.
