Table 3.

The lowest level of conservation (%) for each bNAb epitope-binding motif across subtypes.

Name	Gt1a% Con	Gt1b% Con	Gt2a% Con	Gt2b% Con	Gt2c% Con	Gt3a% Con	Gt3b% Con	Gt4a% Con	Gt4d% Con	Gt6a% Con	Region targeted
HC84.20	98.58	99.73	98.48	99.72	100	99.79	99.75	99.24	100	100	Epitope 2 and 4
AR4A	99.76	99.57	99.8	99.7	100	99.74	98.13	98.13	99.23	100	E1E2
AR5A	99.76	99.57	99.8	99.7	100	99.76	100	98.13	99.23	100	E1E2
95-2	99.66	99.83	100	98.7	100	99.91	99.75	100	100	99.7	Epitope 1
HC33.1	99.55	99.83	100	98.7	100	99.82	99.75	100	99.82	99.7	Epitope 1
HC33.32	99.55	99.83	100	98.7	100	99.82	99.75	100	99.82	99.7	Epitope 1
HC-1	99.78	99.66	92.21	99.72	98.44	99.09	0	99.38	100	100	Epitope 2 and 3
1:7	94.62	98.87	92.21	99.43	98.44	99.09	0	97.5	100	100	Epitope 3
A8	94.62	98.87	92.21	99.43	98.44	99.09	0	97.5	100	100	Epitope 3
Hu5B3.v3	94.46	98.44	93.49	98.7	96.93	96.86	99.51	98.77	99.45	98.81	Epitope 1
AP33	96.98	98.49	97.27	82.94	39.47	84.85	97.8	100	93.91	95.87	Epitope 1
HCV1	96.98	98.49	97.27	82.94	39.47	84.85	97.8	100	93.91	95.87	Epitope 1
H77.39	96.98	98.49	97.27	82.94	39.47	84.85	97.8	100	93.91	95.87	Epitope 1
3/11	96.98	98.49	97.27	82.94	39.47	84.85	97.8	100	93.91	95.87	Epitope 1

Shading denotes > 90% conservation.