Figure 2.

Differential gene-expression of the 112 analyzed genes in infected (n = 6) vs. control mice (n = 5), 1 wpi. The x-axis represents log₂ of expression fold-change between infected and non-infected mice; the y-axis corresponds to the statistical significance, expressed as the negative logarithm of p-values. The red horizontal line indicates the cut-off for the statistical significance p = 0.05. Black vertical lines represent the log₂ FC of −0.6 and 06 (corresponding to FC −1.5 and 1.5 respectively) used as biological threshold to identify differentially expressed genes. The negative values correspond to down-regulated genes (indicated in blue) and the positive values are the up-regulated genes (indicated in red). Black and gray dots represent non-differentially expressed genes.