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Detection of the early phase of esophageal cancer progression into lamina propria mucosae by serum p53 antibody.17 A, Changes in serum p53 antibody levels before and after endoscopic submucosal dissection (ESD) of esophageal squamous cell carcinoma. Carcinoembryonic antigen (CEA) level was continuously negative. B, Resection specimen after ESD of esophageal squamous cell carcinoma. H&E staining in the ESD specimen. C, p53 immunoreactivity in the ESD specimen
